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Depression is seen in more individuals each year, and multiple studies are being performed to figure out if some individuals are genetically more susceptible to this mental illness than others. A common controversy that raises questions in the mental health field is nature vs. nurture. Nurture is the idea that personal experiences and circumstances have more influence on psychological stability. On the other side of the argument is nature, which suggests that DNA is the source of imbalance. The question is, as humans, are we genetically subject to depression, or does our environment have the greatest effect? Or, more simply, is it a combination of both? The results of multiple studies show high evidence that both impact our mental health; however, genetics do play a significant role.

In a major study led by The University of Queensland Australia and The University of North Carolina, clinical depression has been linked to 44 genes. By bringing together various experts on related topics, researchers were able to examine a sample size of 135,000+ people diagnosed with depression and 350,000 mentally stable individuals. In the results of their DNA meta-analysis, the discovery of these 44 genetic risk factors are considered a breakthrough in research for the mentally ill. In addition to genetics, we do need to consider such factors as poverty, trauma etc. as substantial evidence as well.

One potentially important conclusion based on the results of this study is why 60% of depressed individuals don’t respond to pharmacological treatment. Researchers found that many traditional antidepressants target the genes found to be linked to depression. But no one antidepressant targets all 44 genetic associations, and nor will one.

Learn More About the Study

Now that we are beginning to understand the causes of depression, let us consider remedies. One great option for treatment is ketamine infusion therapy. Ketamine works by repairing broken neural connections in the brain, reversing the damage caused by long-term depression. This process allows the brain to form new, healthy connections. Chemically, ketamine transcends genetics, making it extremely useful—and effective for up to 70% of patients. The 30% who do not respond may be due to their DNA.

Contact RestoratIV Wellness

If you or someone you know struggles with clinical depression, request a free consultation at RestoratIV Wellness today. We are happy to answer your questions about ketamine infusion therapy, and help you determine whether ketamine treatments are the right solution for you. We treat patients in southern New Jersey and the greater Philadelphia area. Our clinic leverages state-of-the-art monitoring equipment and employs a team of highly experiences clinicians, ensuring a safe and comfortable infusion experience. Contact us today and start your journey towards health & wellbeing.

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